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Trials and Noteworthy Treatments

  Treatment Next 25 Location Last Updated
Details A Pharmacokinetic and Phase 2 Study of Sunitinib Malate in Recurrent Malignant Gliomas Toronto, Ontario, Canada
Bethesda, MD
New York, NY
Cincinnati,, OH
Columbus, OH 		04/21/2009
Details A Randomized Phase III Study of Temozolomide and Short-Course Radiation Versus Short-Course Radiation Alone In The Treatment of Newly Diagnosed Glioblastoma Multiforme in Elderly Patients Toronto, Ontario, Canada 08/26/2007
Details A Phase II Trial to Evaluate the Effect of Low Dose Temozolomide (TMZ) for 2 Weeks (Pre-Surgery) on Brain Tumor O-6-Methylguanine-DNA Methyltransferase (MGMT) Activity in Patients With Gliomas. Montreal, Canada 08/18/2007
Details Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma Toronto, Ontario, , Canada 05/21/2006
Details A Phase I Study of Tomotherapy in Patients With Benign Brain Tumour Edmonton, Alberta, Canada 05/04/2006
Details Comparative 2-D Tumor Analysis in Familial Gliomas Edmonton, Alberta, Canada 05/04/2006
Details Multimodality Functional Imaging (MRS and Tumor Perfusion) Predicts Tumor Migration, Invasiveness, and Patterns of Failure of Human Gliobastoma Treated With Concurrent Radiation Therapy and Temozolomide Edmonton, Alberta, Canada 11/27/2005
Details Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors , Canada
,
Los Angeles, CA
Palo Alto, CA
Washington, DC
Indianapolis, IN
Boston, MA
Minneapolis, MN
Rochester, MN
Jackson, MS
New York, NY
Syracuse, NY
Cincinnati, OH
Portland, OR
Philadelphia, PA
Pittsburgh, PA
Memphis, TN
Dallas, TX
Houston, TX
Seattle, WA 		11/11/2005

News Stories

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Frequently Asked Questions



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  (0.7967)   My father (78 years old, no other history of illness and no other cancer) has been given a preliminary diagnosis of GBM. The tumor is in the temporal lobe and the size of a grape. There is no neuro-oncologist at this hospital. Should we go through with removal and then seek a second opinion once we have a diagnosis based on a tissue sample? My father seems convinced that there are no treatment options that could be effective considering the size of the tumour.

  (0.7742)   URGENT: Please inform as soon as possible; we have to decide whether we (Sharon Mussen, a 35 year-old social worker, accompanied by one or both parents) should go to Germany for treatment of a high-grade oligoastrocytoma, which has advanced from Grade 2 in 2000, to Grade 3 in 2004, to probably Grade 4 currently. We are awaiting the pathology analysis of the regrown tumor tissue resected last month. It is of life-threatening urgency because the growth seems to be accelerating. Can the receiver of this note, or some other brain tumor physician or researcher to whom you may refer this difficult question, provide us with good OBJECTIVE information and an opinion, very quickly, about the effectiveness of the treatment performed by Dr. Klaus Maier-Hauff (and his clinic at Berlin's Charite Hospital) where it is claimed that a brain-tumor will absorb an applied dosage of sub-microscopic, magnetic, iron-oxide particles which, if we understand correctly, heat and weaken or destroy tumor cells (with no permanent damage to healty tissue or the brain-centered faculties of language, memory, motor/movement, etc). The method has been variously described as Nanotechnology, Nanopartical Application, Thermotherapy, and perhaps other descriptive names. The literature that we have found (mostly at their web-site) is put out by the clinic and/or the German government information services. There is mention, in their web-site literature, of research that is on-going or scheduled to begin. But, even if rigorous medical research has not as yet been completed,we want to base our decision on at least the opinion of knowledgable, non-involved experts. A well-known neurosurgeon here dismissed the idea by telling us that "we tried that method some years ago and found it did not work"; however, as you and we know, nanotechnology is relatively new and, therefore, rapidly improving. Again we need expert, objective opinion. A brief review of the medical situation: In the year 2000, Sharon suffered a grand mal seizure; was taken to

  (0.7742)   My sister was diagnosed with a GBM on her right frontal lobe. She had a craniotomy to remove the tumor but the neurosurgeon said that he was only able to remove about 80% because, when he got in, he noticed that it had crossed the midline. It has been seven weeks since her surgery and she just now started radiation and Temodar. She was developing headaches again and double vision so they took another MRI and it shows that the tumor has grown back. What do they mean by the tumor has crossed the midline? Does this mean that it is inoperable? Can't surgery be performed on each side of the lobe to remove as much as possible? The surgeon never ordered an MRI after the surgery so we really do not know how much was really taken. Is this normal?

  (0.7742)   My father has glioblastoma and the oncologist is suggesting starting the standard round of 30 radiotherapy treatments (following the surgery). It was a 2.5 cm tumor that was mostly removed from the surface of the right frontal lobe. IMRT is not available in our Canadian province. Would radiotherapy using IMRT versus the traditional radiotherapy approach be beneficial for my father in terms of tumor management, and more so in terms of possible side effects? We are debating if we should try to ask for a referral to a center in a different province that does have IMRT available (we are in Canada, so our medical system is a bit different than the states).

  (0.7742)   My 78-year-old mother has just been diagnosed with GBM. She has been seen by a neurosurgeon who was very blunt and said you have lived a good life. He said we could try debulking. We left feeling as if nothing could be gained. I have contacted the brain tTmor clinic at Duke and they currently have her MRI. I have not yet heard from them and I am afraid that time is of the essence. I cannot just sit back and watch this beautiful and much loved woman slip away. We are in Canada and I wonder if you know someplace that we might approach for another consult. Our neurologist is very kind and agreeable to anything we might choose to do.




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