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  • ID is our internal ID - starting with VT.
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Treatment Name: Phase II Clinical Trial of Patients with High-Grade Glioma Treated with Intra-arterial Carboplatin-based Chemotherapy, Randomized to Treatment with or without Delayed Intravenous Sodium Thiosulfate as a Potential Chemoprotectant against Severe Thrombocytopenia
Keywords: High grade glioma, Intra-arterial chemotherapy
Phase: Phase 2
Treatment ID#s: VT1945        
Age Group: Adults Only
Min Karnofsky Score: 70: Cares for self, unable to perform normal activity or to do active work
Conditions: Newly Diagnosed: Y
Recurrent: Y
Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Allowed
This is a randomized study meaning that neither the participant nor their doctor may choose to which treatment group the participant is assigned. All participants of this study receive the chemotherapy drugs carboplatin (intra-arterial), cyclophosphamide (intravenous) and etoposide phosphate (intravenous). Participants will be randomized in two groups. Group 1 will receive the chemotherapy drugs, but not the sodium thiosulfate. Group 2 will receive the chemotherapy drugs, followed by the sodium thiosulfate (intravenous), four and eight hours after the chemotherapy.
Last Updated: 12/02/2009
Tumor Types: Glioblastoma Multiforme
Gliosarcoma
Oligodendroglioma High Grade
Comments: The purpose of this study is to evaluate if the drug called sodium thiosulfate prevents a severe decrease in a particular type of blood cell (platelets) in patients who are being given carboplatin, cyclophosphamide, and etoposide phosphate for the treatment of high-grade glioma.
Treatment Type: Chemotherapy.
Contact: Hatton Research Center
Robert Albright, Jr, MD
Neuro Oncologist
375 Dixmyth Ave
Cincinnati, OH 45220
Phone:513-862-2251
Fax: 513-852-3091
Click here to send an email
Website: www.Hattonresearch.org


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